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  2. Glomerular filtration rate - Wikipedia

    en.wikipedia.org/wiki/Glomerular_filtration_rate

    Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).

  3. Race adjustment - Wikipedia

    en.wikipedia.org/wiki/Race_adjustment

    The estimated glomerular filtration rate (eGFR) is a measure of kidney function. [6] Adding a race adjustment to kidney algorithms results in higher eGFR values in people identified as black. [7] [8] [9] Reasons for this vary, but it is thought to partially stem from the notion that Black persons are more muscular. [8]

  4. Epidermal growth factor receptor - Wikipedia

    en.wikipedia.org/wiki/Epidermal_growth_factor...

    Mutations that lead to EGFR overexpression (known as upregulation or amplification) have been associated with a number of cancers, including adenocarcinoma of the lung (40% of cases), anal cancers, [18] glioblastoma (50%) and epithelian tumors of the head and neck (80–100%). [19]

  5. EGFR - Wikipedia

    en.wikipedia.org/wiki/EGFR

    EGFR may refer to: Epidermal growth factor receptor (EGFR), a transmembrane receptor protein in humans Estimated glomerular filtration rate (eGFR), a measure of renal function

  6. Chronic kidney disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_kidney_disease

    Hypocalcemia results from 1,25 dihydroxyvitamin D 3 deficiency (caused by high FGF-23 and reduced kidney mass) [30] and the skeletal resistance to the calcemic action of parathyroid hormone. [31] Osteocytes are responsible for the increased production of FGF-23, which is a potent inhibitor of the enzyme 1-alpha-hydroxylase (responsible for the ...

  7. Body roundness index - Wikipedia

    en.wikipedia.org/wiki/Body_roundness_index

    BRI was first reported in 2013 by the mathematician Diana Thomas and colleagues in an analysis of three databases from studies of demographics, anthropometrics, fat mass, and visceral fat volume. [ 1 ] [ 2 ] Thomas visualized the human body shape as an egg or ellipse rather than as the cylinder model that is envisioned in the concept of the BMI.

  8. Genetics of obesity - Wikipedia

    en.wikipedia.org/wiki/Genetics_of_obesity

    Although it does not play a role in the formation of fat itself, it does determine the location on the body where this fat is stored. SH2B1 [23] 16p11.2 MTCH2 [23] 11p11.2 PCSK1 [23] 5q15-q21 NPC1 [24] 18q11-q12 LYPLAL1 [25] 616548: 1q41 Disputed metabolic function of being either a lipase [26] or a short-chain carboxylesterase. [27] CB 1 [28 ...

  9. Obesity in Canada - Wikipedia

    en.wikipedia.org/wiki/Obesity_in_Canada

    Share of adults that are obese, 1975 to 2016. Obesity in Canada is a growing health concern, which is "expected to surpass [a] smoking as the leading cause of preventable morbidity and mortality" and represents a burden [b] of Can$3.96 (US$3.04/€2.75) billion on the Canadian economy each year."