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2. Treatment-resistant depression - Wikipedia

   en.wikipedia.org/wiki/Treatment-resistant_depression

   Ketamine has been tested as a rapid-acting antidepressant [13] for treatment-resistant depression in bipolar disorder, and major depressive disorder. [14] Spravato, a nasal spray form of esketamine, was approved by the FDA in 2019 for use in treatment-resistant depression when combined with an oral antidepressant. [15] [16]

3. Breakthrough antidepressants with fewer side effects could ...

   www.aol.com/finance/breakthrough-antidepressants...

   The FDA approved Johnson & Johnson’s drug for treatment-resistant depression in 2019. Esketamine is derived from a pediatric anesthetic called ketamine. ... FDA guidelines recommend patients ...

4. Management of depression - Wikipedia

   en.wikipedia.org/wiki/Management_of_depression

   Stephen M. Stahl, renowned academician in psychopharmacology, has stated resorting to a dynamic psychostimulant, in particular, d-amphetamine is the "classical augmentation strategy for treatment-refractory depression". [84] However, the use of stimulants in cases of treatment-resistant depression is relatively controversial. [85] [86]

5. Ketamine-assisted psychotherapy - Wikipedia

   en.wikipedia.org/wiki/Ketamine-assisted...

   Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]

6. Vagus nerve stimulation may relieve treatment-resistant ... - AOL

   www.aol.com/those-treatment-resistant-depression...

   With treatment-resistant depression affecting about 30% of an estimated 21 million adults with major depressive disorder, the findings are “really promising,” Badran said.

7. What you need to know about 'treatment-resistant' depression ...

   www.aol.com/news/know-treatment-resistant...

   In the immediate aftermath of a high-profile suicide of a beloved celebrity like Naomi Judd, calls to suicide-prevention hotlines tend to increase.