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Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
When Grayson Smith, a 23-year-old woman from Texas, started feeling sluggish and tired in the afternoons, she said a blood test she had low testosterone, a sex hormone traditionally associated ...
Estradiol valerate has been used at very high doses of 40 to 100 mg once per week in women and men, ... 40–60 d; 25–50 ≈ 60–120 d ... in hormone therapy for ...
25–50 mg 1x/6–12 weeks Prasterone enanthate a: Gynodian Depot: Oil solution: 200 mg 1x/4–6 weeks Implant: Testosterone: Testopel: Pellet: 50–100 mg 1x/3–6 months Notes: Premenopausal women produce about 230 ± 70 μg testosterone per day (6.4 ± 2.0 mg testosterone per 4 weeks), with a range of 130 to 330 μg per day (3.6–9.2 mg per ...
In 2002, the Women's Health Initiative study (WHI) that was designed to demonstrate additional benefits of conventional hormone therapy (study participants were given Prempro or a placebo) was terminated prematurely after preliminary data indicated small increases in the risks of breast cancer, heart attack and stroke in older women using ...
Plasma levels of DHEA in adult men are 10 to 25 nM, in premenopausal women are 5 to 30 nM, and in postmenopausal women are 2 to 20 nM. [25] Conversely, DHEA-S levels are an order of magnitude higher at 1–10 μM. [25] Levels of DHEA and DHEA-S decline to the lower nanomolar and micromolar ranges in men and women aged 60 to 80 years. [25]
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