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Dexamethasone is a fluorinated glucocorticoid medication [10] used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease (COPD), croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), [11] and along with antibiotics in tuberculosis. [10]
Dexamethasone acefurate; Dexamethasone acetate (flumeprednisolone) Dexamethasone cipecilate; Dexamethasone diethylaminoacetate; Dexamethasone dipropionate; Dexamethasone isonicotinate; Dexamethasone linoleate; Dexamethasone metasulphobenzoate; Dexamethasone palmitate; Dexamethasone phosphate; Dexamethasone pivalate; Dexamethasone succinate ...
Dexamethasone – a synthetic glucocorticoid binds more powerfully to the glucocorticoid receptor than cortisol does. Dexamethasone is based on the cortisol structure but differs at three positions (extra double bond in the A-ring between carbons 1 and 2 and addition of a 9-α-fluoro group and a 16-α-methyl substituent).
Steroid ring system. This is a list of corticosteroids ( glucocorticoids and mineralocorticoids ) or derivatives of cortisol ( hydrocortisone ). Most esters of these corticosteroids are not included in this list; for esters, see here instead.
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism ...
Several U.S. hospitals in states with fresh surges of COVID-19 cases have started treating their sickest patients with dexamethasone.
Dexamethasone is an exogenous steroid that provides negative feedback to the pituitary gland to suppress the secretion of adrenocorticotropic hormone (ACTH). Specifically, dexamethasone binds to glucocorticoid receptors in the anterior pituitary gland, which lie outside the blood–brain barrier, resulting in regulatory modulation. [3]
List of steroidogenesis inhibitors – steroidogenesis inhibitors, or inhibitors of steroid biosynthesis and metabolism; As well as lists of steroid esters, including: List of androgen esters – androgen esters; List of estrogen esters – estrogen esters; List of progestogen esters – progestogen esters; List of corticosteroid esters ...