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  2. Crohn's disease - Wikipedia

    en.wikipedia.org/wiki/Crohn's_disease

    While the exact cause or causes are unknown, Crohn's disease seems to be due to a combination of environmental factors and genetic predisposition. [96] Crohn's is the first genetically complex disease in which the relationship between genetic risk factors and the immune system is understood in considerable detail. [ 97 ]

  3. Gallstone - Wikipedia

    en.wikipedia.org/wiki/Gallstone

    Gallbladder and biliary-related diseases occurred in about 104 million people (1.6% of people) in 2013 and resulted in 106,000 deaths. [8] [9] Gallstones are more common among women than men and occur more commonly after the age of 40. [2] Gallstones occur more frequently among certain ethnic groups than others. [2]

  4. Primary sclerosing cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_sclerosing_cholangitis

    The exact cause of primary sclerosing cholangitis is unknown, and its pathogenesis is improperly understood. [1] Although PSC is thought to be caused by autoimmune disease, it does not demonstrate a clear response to immunosuppressants. Thus, many experts believe it to be a complex, multifactorial (including immune-mediated) disorder and ...

  5. Feeling overwhelmed by a Crohn’s disease diagnosis? Try these doctor-recommended first steps. You Just Found Out You Have Crohn's Disease—Here Are 6 Things Gastroenterologists Recommend You Do ...

  6. Inflammatory bowel disease - Wikipedia

    en.wikipedia.org/wiki/Inflammatory_bowel_disease

    Physicians tell the difference between Crohn's disease and UC by the location and nature of the inflammatory changes. Crohn's can affect any part of the gastrointestinal tract, from mouth to anus (skip lesions), although a majority of the cases start in the terminal ileum. Ulcerative colitis, in contrast, is restricted to the colon and the ...

  7. Ascending cholangitis - Wikipedia

    en.wikipedia.org/wiki/Ascending_cholangitis

    Bile duct obstruction, which is usually present in acute cholangitis, is generally due to gallstones. 10–30% of cases, however, are due to other causes such as benign stricturing (narrowing of the bile duct without an underlying tumor), postoperative damage or an altered structure of the bile ducts such as narrowing at the site of an anastomosis (surgical connection), various tumors (cancer ...

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