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Antiplatelet medications are one of the primary recommendations for treatment of both stable [4] and unstable [5] ischemic heart disease.Most commonly, aspirin is used as a single medication in cases of uncomplicated stable angina, and in some cases of unstable angina.
Aspirin is an effective analgesic for acute pain, although it is generally considered inferior to ibuprofen because aspirin is more likely to cause gastrointestinal bleeding. [90] Aspirin is generally ineffective for those pains caused by muscle cramps , bloating , gastric distension , or acute skin irritation. [ 91 ]
Additionally, aspirin induces the formation of NO-radicals in the body, which have been shown in mice to have an independent mechanism of reducing inflammation. This reduces leukocyte adhesion, which is an important step in immune response to infection. There is currently insufficient evidence to show that aspirin helps to fight infection. [18]
Janet O'Mahony, a Baltimore-area internal medicine doctor at Mercy Medical Center, tells Yahoo Life: “Where aspirin is used more commonly these days is as an antiplatelet agent,” or blood ...
The second generation thienopyridine P2Y 12 receptor blocker clopidogrel is an effective antiplatelet agent useful for treatment of ischemic cerebrovascular, cardiac and peripheral arterial release. [27] Like other thienopyridine drugs, the drug was often combined with aspirin in clinical use. [23]
An antithrombotic agent is a drug that reduces the formation of blood clots (). [1] [2] Antithrombotics can be used therapeutically for prevention (primary prevention, secondary prevention) or treatment of a dangerous blood clot (acute thrombus).
Anticoagulants are considered more aggressive than antiplatelet drugs. [34] Anticoagulants work by interfering with various clotting factors to lengthen the time for coagulation. This can be achieved by either reducing the formation of bioactive clotting factors or accelerating the inactivation of clotting factors.
Acetylsalicylic acid (Aspirin) - An extremely common NSAID that has anticoagulant effects; Dipyridamole, a drug that inhibits platelet activation [2] when given chronically and causes vasodilation when given at high doses over short time.
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