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The infection can spread through the blood or lymphatic system, causing abscesses to form in other lymph nodes or internal organs throughout the body. Most commonly affected organs are the liver, lungs, kidneys and lymph nodes associated these organs. Abscesses grow gradually over time, and if they are located close to the skin, rupture is common.
They are caused by Yersinia pestis bacteria spreading from flea bites through the bloodstream to the lymph nodes, where the bacteria replicate, causing the nodes to swell. [3] Plague buboes may turn black and necrotic , rotting away the surrounding tissue, or they may rupture, discharging large amounts of pus . [ 3 ]
The tonsils and cervical lymph nodes in these cases are hyperplasic and contain mixtures of normal-appearing lymphocytes, activated lymphocytes, plasma cells, and Reed–Sternberg-like cells. [16] Many of these normal-appearing and activated B cells and a small percentage of the tissue's T and NK cells are EBV+ with the virus being mostly in ...
Peripheral tuberculous lymphadenitis (or tuberculous adenitis) is a form of tuberculosis infection occurring outside of the lungs. [1] In general, it describes tuberculosis infection of the lymph nodes, leading to lymphadenopathy. When cervical lymph nodes are affected, it is commonly referred to as "Scrofula."
An estimated 58,000 to 80,000 children under age 5 are hospitalized in the U.S. each year due to this respiratory infection. ... Swollen lymph nodes in the front of the neck. ... in the lungs ...
M. avium typically causes unilateral swelling of one of the lymph nodes of the neck. This node is firm at the beginning, but a 'collar-stud' abscess is formed eventually, which is a characteristic blue-purple in colour with multiple discharging sinuses.
In the case of mediastinal lymphadenopathy, the enlarged lymph node causes compression of the lymphatic channels and thoracic duct. This impedes the centripetal drainage of the flow of lymph from the edges of the lung parenchyma and pleural surfaces. This causes the chyle to ooze extensively into the pleural cavity, leading to a chylothorax.
Caseous necrosis in the kidney. In caseous necrosis no histological architecture is preserved (unlike with coagulative necrosis). [5] [6] On microscopic examination with H&E staining, the area is acellular, characterised by amorphous, roughly granular eosinophilic debris of now dead cells, [6] also containing interspearsed haematoxyphilic remnants of cell nucleus contents. [5]