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[286] [287] [288] Vaginal micronized progesterone gels and capsules were introduced for medical use under brand names such as Utrogestan and Crinone in the early 1990s. [ 103 ] [ 289 ] Progesterone was approved in the United States as a vaginal gel in 1997 and as a vaginal insert in 2007.
Progesterone is available for vaginal administration in the form of capsules (Utrogestan), gels (Crinone, Prochieve), suppositories (Cyclogest), inserts/tablets (Endometrin, Lutinus), and rings (Fertiring, Progering). [150] [151] [152] In addition, oral micronized progesterone capsules have been administered vaginally with success. [153]
Estradiol/progesterone (TX-001HR), a combination of estradiol and progesterone in oil-filled capsules, is currently pending approval. [45] Estradiol and norgestimate (Prefest; 1 mg / 90 μg) was previously available in the U.S. but was discontinued.
It is used as an administration method for issues related to women's health, such as contraception. [5] Medicines primarily delivered by intravaginal administration include vaginally administered estrogens and progestogens (a group of hormones including progesterone ), and antibacterials and antifungals to treat bacterial vaginosis and yeast ...
Progestogens are used in a variety of different forms of hormonal birth control for females, including combined estrogen and progestogen forms like combined oral contraceptive pills, combined contraceptive patches, combined contraceptive vaginal rings, and combined injectable contraceptives; and progestogen-only forms like progestogen-only ...
Ulipristal acetate, sold under the brand name Ella among others, is a medication used for emergency contraception (birth control) and uterine fibroids. [1] [7] [8] As emergency contraception it should be used within 120 hours of vaginally penetrating intercourse. [1] For fibroids it may be taken for up to six months. [9] It is taken by mouth. [1]