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Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs. The most common and most severe form is systemic lupus erythematosus.
Neonatal lupus is the occurrence of SLE symptoms in an infant born from a mother with SLE, most commonly presenting with a rash resembling discoid lupus erythematosus, and sometimes with systemic abnormalities such as heart block or enlargement of the liver and spleen. [53] Neonatal lupus is usually benign and self-limited. [53]
For diagnosis of NPSLE, it must be determined whether neuropsychiatric symptoms are indeed caused by SLE, whether they constitute a separate comorbid condition, or whether they are an adverse effect of disease treatment. In addition, onset of neuropsychiatric symptoms may happen prior to the diagnosis of lupus. [7]
These deposits and inflammation seem to be the cause of most of the symptoms of lupus, which remember is a type III hypersensitivity reaction. Many patients, though, also develop antibodies targeting other cells like red and white blood cells, and molecules like various phospholipids, which can mark them for phagocytosis and destruction ...
Acute cutaneous lupus erythematosus is a cutaneous condition characterized by a bilateral malar rash (also known as a "butterfly rash") and lesions that tend to be transient, and that follow sun exposure. [1] The acute form is distinct from chronic and subacute cutaneous lupus erythematosus, which may have different types of skin lesions. [2]
cSLE, Juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus: Specialty: Rheumatology: Usual onset: Children up to 17 years old: Types: Early-onset SLE is a type of cSLE that occurs in children up to 5 years old. It tends to be more severe than cSLE in older children. Causes
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