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[20] [22] About 84.9% of dental practitioners among those attending a health screening program in the annual ADA session in San Francisco, California, were found to restore teeth with 100–200 dental amalgam restorations in a week, and about 4.2% did a minimum of 50 dental amalgam fillings in a week. [22]
The effect of the developmental toxicants depends on the type of substance, dose, duration, and time of the exposure. The first few weeks of embryogenesis in humans is more susceptible to these agents. The embryogenesis is the most crucial time for the action of any teratogenic substances to result in birth defects.
Disclosing tablets are chewable tablets that make dental plaque visible. The tablets, sold over the counter in many countries, contain a dye (typically a vegetable dye, such as Phloxine B) that stains the plaque a bright color (typically red or blue). After brushing, one chews a tablet and rinses. Colored stains on the teeth indicate areas ...
Reproductive toxicity refers to the potential risk from a given chemical, physical or biologic agent to adversely affect both male and female fertility as well as offspring development. [1] Reproductive toxicants may adversely affect sexual function, ovarian failure, fertility as well as causing developmental toxicity in the offspring.
While this is still part of the teratological evaluation procedures today, the field of Teratology is moving to a more molecular level, seeking the mechanism(s) of action by which these agents act. One example of this is the use of mammalian animal models to evaluate the molecular role of teratogens in the development of embryonic populations ...
Susceptibility to teratogenesis varies with the developmental stage at the time of exposure to an adverse influence. There are critical periods of susceptibility to agents and organ systems affected by these agents. Teratogenic agents act in specific ways on developing cells and tissues to initiate sequences of abnormal developmental events.
Fetal hydantoin syndrome, also called fetal dilantin syndrome, is a group of defects caused to the developing fetus by exposure to teratogenic effects of phenytoin. Dilantin is the brand name of the drug phenytoin sodium in the United States, commonly used in the treatment of epilepsy .
In dentistry, phenoxymethyl penicillin is used as it is acid-resistant and can be administered orally. Its common uses include treatment against acute oral infections such as dental abscesses, [5] pericoronitis, salivary gland infections and post-extraction infection. The main disadvantage however, is that patients can be allergic to penicillin ...