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Those on topiramate started on a daily dose of 16mg and gradually moved up to a daily dose of either 64mg, 96mg, 192mg or 384mg. At the end of the study, the placebo group had a mean weight loss ...
Phentermine is a stimulant and appetite suppressant. [3] Topiramate is an anticonvulsant that has weight loss side effects. [ 3 ] The exact mechanism of action for both drugs is unknown.
This is a combination of an appetite suppressant called phentermine and an anticonvulsant called topiramate. Phentermine-topiramate is effective for weight loss and seems to reduce blood pressure ...
Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant effects. [8] [9] [10] Chemically, it is a substituted amphetamine. [11] Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3]
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They worked primarily by suppressing appetite, and had other beneficial effects such as increased alertness. Use of amphetamines increased over the subsequent decades, including Obetrol and culminating in the "rainbow diet pill" regime. [38] This was a combination of multiple pills, all thought to help with weight loss, taken throughout the day.
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