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Sepsis requires immediate treatment with intravenous fluids and antimicrobial medications. [1] [5] Ongoing care and stabilization often continues in an intensive care unit. [1] If an adequate trial of fluid replacement is not enough to maintain blood pressure, then the use of medications that raise blood pressure becomes necessary. [1]
The Surviving Sepsis Campaign (SSC) is a global initiative to bring together professional organizations in reducing mortality from sepsis.The purpose of the SSC is to create an international collaborative effort to improve the treatment of sepsis and reduce the high mortality rate associated with the condition.
Infection prevention and control is the discipline concerned with preventing healthcare-associated infections; a practical rather than academic sub-discipline of epidemiology. In Northern Europe , infection prevention and control is expanded from healthcare into a component in public health , known as "infection protection" ( smittevern ...
“Sepsis usually begins with an infection, for example in the chest, skin, urine or meningitis, but in the early stages symptoms can be vague and hard even for doctors and nurses to recognise.
Septic shock is a result of a systemic response to infection or multiple infectious causes. The precipitating infections that may lead to septic shock if severe enough include but are not limited to appendicitis, pneumonia, bacteremia, diverticulitis, pyelonephritis, meningitis, pancreatitis, necrotizing fasciitis, MRSA and mesenteric ischemia.
In septic patients, these clinical signs can also be seen in other proinflammatory conditions, such as trauma, burns, pancreatitis, etc. A follow-up conference, therefore, decided to define the patients with a documented or highly suspicious infection that results in a systemic inflammatory response as having sepsis. [18]
Control of inflammation, vascular function and coagulation to correct pathological differences in blood flow and microvascular shunting has been pointed to as a potentially important adjunct goal in the treatment of distributive shock. [2] People with septic shock are treated with antimicrobial drugs to treat the causative infection. [12]
Sepsis Alliance is a non-profit organization dedicated to raising awareness of sepsis. This awareness is accomplished through a variety of methods, including healthcare professional education programs, outreach to the general population, and lobbying for regulatory measures which improve outcomes for individuals with sepsis. [1]