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Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of episodic and chronic constipation and for the management of neurogenic bowel dysfunction, as well as part of bowel preparation before medical examinations, such as for a colonoscopy.
Dulcolax, a trade name of bisacodyl, a stimulant laxative drug that increases bowel movement Dulcolax Balance, a trade name of macrogol , an osmotic laxative Dulcolax Stool Softener, a trade name of dioctyl sodium sulfosuccinate , a common ingredient in products such as laxatives
Prucalopride (brand name Resolor) is a current drug approved for use in the EU since October 15, 2009, [17] in Canada (brand name Resotran) since December 7, 2011, [18] and in the United States since December 2018.
Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as an emollient laxative and as stool softeners, by mouth or rectally. [1]
For both adults and children, glycerine or bisacodyl suppositories provide an alternative to enemas. [13] The first-choice maintenance treatment advised for functional constipation is osmotic laxatives. [14] [16] Other often used laxatives include milk of magnesia (magnesium hydroxide) and mineral oil, a lubricant. [13]
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Sodium citrate saline is one of the most effective osmotic laxatives (secondary in action only to magnesium citrate). [8] Its laxative action is the result of osmotic imbalance that extracts bound water from stool and pulls it back into the large bowel.
Sodium picosulfate is a prodrug. [5] It has no significant direct physiological effect on the intestine; however, it is metabolised by gut bacteria into the active compound 4,4'-dihydroxydiphenyl-(2-pyridyl)methane (DPM, BHPM).