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Platelets collected by using apheresis at an American Red Cross donation center. Not all platelet transfusions use platelets collected by automated apheresis. The platelets can also be separated from donations of whole blood collected in a traditional blood donation, but there are several advantages to separating the platelets at the time of collection.
For apheresis platelet donation the donor's pre platelet count should be above 150 x 10^9/L. For apheresis plasma donation, the donor's total protein level should be greater than 60 g/L. For double red cell apheresis, donors of either gender require a minimum hemoglobin level of 14.0 g/dl. [15]
Blood donation pictogram Blood donation center at the University Hospital of Basel, Switzerland. From left to right: Two cell separators for apheresis, secluded office for pre-donation blood pressure measurement and blood count, and on the right, chairs for whole blood donations. A patient donating blood at a Blood Bank in Córdoba, Argentina
Erythrocytapheresis is an apheresis procedure by which erythrocytes (red blood cells) are separated from whole blood. It is an extracorporeal blood separation method whereby whole blood is extracted from a donor or patient, the red blood cells are separated, and the remaining blood is returned to circulation.
An exchange transfusion is a blood transfusion in which the patient's blood or components of it are exchanged with (replaced by) other blood or blood products. [1] The patient's blood is removed and replaced by donated blood or blood components.
During apheresis treatments adverse events such as anemia, citrate toxicity, central venous catheter safety and infections are notable. [ 2 ] [ 3 ] [ 8 ] Anemia : Anemia is related to numerous and/or consecutive treatments and/or large extracorporeal circuits that reduces the hemoglobin levels in pediatric patients.
Platelets are either isolated from collected units of whole blood and pooled to make a therapeutic dose, or collected by platelet apheresis: blood is taken from the donor, passed through a device which removes the platelets, and the remainder is returned to the donor in a closed loop. The industry standard is for platelets to be tested for ...
Platelet swirling is caused by light diffraction due to the alignment of normal disc-shaped platelets. These discs align light that is diffracted, creating a cloud- or swirl-like appearance. [citation needed] Results of a platelet swirling test are recorded as positive or extensive swirl, moderate or intermediate swirl, and absent or negative ...