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The mucosa is the innermost layer of the gastrointestinal tract. It surrounds the cavity of the tract and comes into direct contact with digested food . The mucosa is made up of three layers: [1] The epithelium is the innermost layer. It is where most digestive, absorptive and secretory processes occur.
The small intestine is the site where most of the nutrients from ingested food are absorbed. The inner wall, or mucosa, of the small intestine, is lined with intestinal epithelium, a simple columnar epithelium. Structurally, the mucosa is covered in wrinkles or flaps called circular folds, which are considered permanent features in the mucosa.
The intestinal epithelium is the single cell layer that forms the luminal surface (lining) of both the small and large intestine (colon) of the gastrointestinal tract. Composed of simple columnar epithelium its main functions are absorption, and secretion. Useful substances are absorbed into the body, and the entry of harmful substances is ...
The intestinal mucosal barrier is a heterogeneous entity composed of physical, biochemical, and immune elements elaborated by the intestinal mucosa. The central component is the intestinal epithelial layer, which provides physical separation between the lumen and the body. The secretion of various molecules into the lumen reinforces the barrier ...
Intestinal glands are found in the epithelia of the small intestine, namely the duodenum, jejunum, and ileum, and in the large intestine (colon), where they are sometimes called colonic crypts. Intestinal glands of the small intestine contain a base of replicating stem cells , Paneth cells of the innate immune system , and goblet cells , which ...
The duodenum precedes the jejunum and ileum and is the shortest part of the small intestine. In human beings, the duodenum is a hollow jointed tube about 25–38 centimetres (10–15 inches) long connecting the stomach to the middle part of the small intestine. [4] [5] It begins with the duodenal bulb and ends at the suspensory muscle of ...
It forms an essential layer in the colon and in the small intestine that helps reduce intestinal inflammation by decreasing bacterial interaction with intestinal epithelial cells. [21] The layer of mucus of the gastric mucosa lining the stomach is vital to protect the stomach lining from the highly acidic environment within it. [22]
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