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The protein acts as an inhibitor of vascular mineralization and plays a role in bone organization. [5] [6] MGP is found in a number of body tissues in mammals, birds, and fish. Its mRNA is present in bone, cartilage, heart, and kidney. [7] It is present in bone together with the related vitamin K2-dependent protein osteocalcin.
Vitamin K is a family of structurally similar, fat-soluble vitamers found in foods and marketed as dietary supplements. [1] The human body requires vitamin K for post-synthesis modification of certain proteins that are required for blood coagulation ("K" from Danish koagulation, for "coagulation") or for controlling binding of calcium in bones and other tissues. [2]
Vitamin K is vital for blood clotting factors and is partially responsible for this injury to stop bleeding and to heal." ... Older research indicates it improves bone mineral density. "Vitamin K ...
[2] [3] [6] Vitamin K can be delivered into the body via the oral, subcutaneous, intramuscular, or intravenous routes of administration. [7] Vitamin K can influence bone health, coagulation, and insulin sensitivity, but it can also be effected by bariatric surgery which can result in vitamin K deficiency.
Up to 31 percent of adults may be insufficient in vitamin K, and that could affect your bones, joints, ... To avoid a vitamin K deficiency, eat foods high in vitamin K1, including leafy green ...
Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a small (49-amino-acid [5]) noncollagenous protein hormone found in bone and dentin, first identified as a calcium-binding protein. [6] Because osteocalcin has gla domains, its synthesis is vitamin K2-dependent.