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The miRBase registry provides a centralised system for assigning new names to microRNA genes. [6] miRBase grew from the microRNA registry resource set up by Sam Griffiths-Jones in 2003. [7] According to Ana Kozomara and Sam Griffiths-Jones miRBase has five aims: [1] To provide a consistent naming system for microRNAs
miRBase is considered to be the gold-standard miRNA database—it stores miRNA sequences detected by thousand of experiments. In this database each miRNA is associated with a miRNA precursor and with one or two mature miRNA (-5p and -3p). In the past it had always been said that the same miRNA precursor generates the same miRNA sequences.
This microRNA database and microRNA targets databases is a compilation of databases and web portals and servers used for microRNAs and their targets. MicroRNAs (miRNAs) represent an important class of small non-coding RNAs (ncRNAs) that regulate gene expression by targeting messenger RNAs.
Many mammalian genomes encode four closely related miR-29 precursors that are transcribed in two transcriptional units. For example, human miR-29a and miR-29b-1 are processed from an intron of a long non-coding transcript pri-miRNA (lnc-pri-miRNA) LOC646329 from chromosome 7. miR-29b-2 (identical in sequence to miR-29b-1) and miR-29c are co-transcribed from chromosome 1.
MMP (file format) – Mind Manager mind map file; MUP – File type used by MindMup to export editable Mind Maps; TPC (file format) – 3D Topicscape file, produced when an inter-Topicscape topic link file is exported to Windows; used to permit round-trip (export Topicscape, change files and folders as desired, re-import to 3D Topicscape)
Example of a flat file model [1] A flat-file database is a database stored in a file called a flat file. Records follow a uniform format, and there are no structures for indexing or recognizing relationships between records. The file is simple. A flat file can be a plain text file (e.g. csv, txt or tsv), or a binary file. Relationships can be ...
As miR recognition elements are typically found in the 3' UTR of the target gene mRNA, bioinformatics alone can identify putative miR-92 targets using resources such as miRGen database. In one report, miRanda software found 300 different genes that have putative miR-92a binding sites conserved among Homo sapiens, Mus musculus, and Rattus ...
The original dbm library and file format was a simple database engine, originally written by Ken Thompson and released by AT&T in 1979. The name is a three-letter acronym for DataBase Manager, and can also refer to the family of database engines with APIs and features derived from the original dbm.