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The wrong decision can be catastrophic: a vegetative cell will die if the conditions are too harsh, while bacteria forming spores in an environment which is conducive to vegetative growth will be out competed. [3] In short, initiation of sporulation is a very tightly regulated network with numerous checkpoints for efficient control. [citation ...
The process of serial passage yields a live vaccine. There are both advantages and disadvantages to this. Most notably, live vaccines are sometimes more effective and more long-lasting than inactivated or other types of vaccines. [10] [11] However, just as the virus evolved to become attenuated, it may reverse-evolve in the host, leading to ...
Under conditions of starvation, especially the lack of carbon and nitrogen sources, a single endospore forms within some of the bacteria through a process called sporulation. [15] When a bacterium detects environmental conditions are becoming unfavourable it may start the process of endosporulation, which takes about eight hours.
Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating the body's adaptive immunity, they help prevent sickness from an infectious disease.
Flu vaccines used during the flu in 2009. This is a list of vaccine-related topics.. A vaccine is a biological preparation that improves immunity to a particular disease.A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe or its toxins.
The final stage in vaccine manufacture before distribution is fill and finish, which is the process of filling vials with vaccines and packaging them for distribution. Although this is a conceptually simple part of the vaccine manufacture process, it is often a bottleneck in the process of distributing and administering vaccines. [132] [133] [134]
C. botulinum is a Gram-positive, rod-shaped, spore-forming bacterium. [1] It is an obligate anaerobe, the organism survives in an environment that lacks oxygen.However, C. botulinum tolerates traces of oxygen due to the enzyme superoxide dismutase, which is an important antioxidant defense in nearly all cells exposed to oxygen. [7]
Vaccination against vaccine-preventable diseases is a major relief of disease burden even though it usually cannot eradicate a disease. Vaccines against microorganisms that cause diseases can prepare the body's immune system, thus helping to fight or prevent an infection.