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Dexamethasone is a fluorinated glucocorticoid medication [10] used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease (COPD), croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), [11] and along with antibiotics in tuberculosis. [10]
Most esters of these corticosteroids are not included in this list; for esters, see here instead. The most common structural modifications in synthetic corticosteroids include 1(2)- dehydrogenation , 6α-, 9α-, 16α-, and 16β- substitution (with a halogen or methyl group ), 16α,17α- acetonidation , and 17α- and 21- esterification .
Other non-FDA-approved uses include actinic keratosis, amyloidosis, Peyronie's disease, and psoriasis. Dexamethasone and betamethasone in premature labor, to enhance pulmonary maturation of the fetus. [7] Doxepin has been used to treat angiodema and severe allergic reactions due to its strong antihistamine properties. [8]
Beclometasone dipropionate, an example of a widely used corticosteroid ester. Note the propionate groups at the C17α and C21α positions (top right corner). This is a list of corticosteroid esters , including esters of steroidal glucocorticoids and mineralocorticoids .
This particular drug has been over-the-counter in the U.K. since 2004 but has failed to get approval for unrestricted usage in the United States. ... the FDA did approve the progestin-only Opill ...
Trade names: Levodexa: Routes of ... ATC code: S01CA01 ; Legal status; Legal status: CA: ℞-only [1] [2] Dexamethasone ... is a fixed-dose combination medication ...
Long-term use of topical steroids can lead to secondary infection with fungus or bacteria (see tinea incognito), skin atrophy, telangiectasia (prominent blood vessels), skin bruising and fragility. [11] The use of the finger tip unit may be helpful in guiding how much topical steroid is required to cover different areas of the body.
'P' medications are reserved from the GSL list as they are either associated with a need for advice on use, or used in conditions which may require referral to a medical prescriber. Suitably trained counter assistants may sell a 'P' medication under the supervision of a pharmacist and will ask questions to determine if the customer needs to be ...