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The basic process by which imaging particle analysis is carried out is as follows: A digital camera captures an image of the field of view in the optical system. A gray scale thresholding process is used to perform image segmentation, segregating out the particles from the background, creating a binary image of each particle. [4] [5] [6]
The laminin B domain (also known as domain IV) is an extracellular module of unknown function. It is found in a number of different proteins that include, heparan sulphate proteoglycan from basement membrane, a laminin-like protein from Caenorhabditis elegans and laminin. Laminin IV domain is not found in short laminin chains (alpha4 or beta3).
Confocal microscopic analysis of a dermal fibroblast in primary culture from a control (a and b) and the subject with HGPS (c and d). Labelling was performed with anti-lamin A/C antibodies. Note the presence of irregularly shaped nuclear envelopes in many of the subject's fibroblasts
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Associated particle imaging (API), sometimes referred to as the tagged neutron method (TNM), [1] [2] is a three dimensional imaging technique that maps the distribution of elements within an object. In associated particle imaging, deuterium-tritium fusion reactions each produce a fast neutron and an associated particle (such as an alpha ...
Particle size analyzers are used also in biology to measure protein aggregation. Particle size distribution of antiviral vaccines subjected to cold-chain disruptions, analyzed by Dynamic Light Scattering (DLS) DLS is a particularly appreciated technique for the characterization of nanoparticles designed for drug delivery, such as vaccines.
Nanoparticle tracking analysis (NTA) is a method for visualizing and analyzing particles in liquids that relates the rate of Brownian motion to particle size. The rate of movement is related only to the viscosity and temperature of the liquid; it is not influenced by particle density or refractive index .
The various branches of the DEM family are the distinct element method proposed by Peter A. Cundall and Otto D. L. Strack in 1979, [5] the generalized discrete element method, [6] the discontinuous deformation analysis (DDA) and the finite-discrete element method concurrently developed by several groups (e.g., Munjiza and Owen).