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For example, all laminin alpha-chains have five laminin G domains, all collagen family proteins have one laminin G domain, the CNTNAP proteins have four laminin G domains, while neurexin 1 and 2 each hold six laminin G domains. On average, approximately one quarter of the proteins that hold laminin G domains is taken up by these laminin G ...
16776 Ensembl ENSG00000130702 ENSMUSG00000015647 UniProt O15230 Q61001 RefSeq (mRNA) NM_005560 NM_001081171 RefSeq (protein) NP_005551 NP_001074640 Location (UCSC) Chr 20: 62.31 – 62.37 Mb Chr 2: 179.82 – 179.87 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Laminin subunit alpha-5 is a protein that in humans is encoded by the LAMA5 gene. Function Components of the extracellular ...
Confocal microscopic analysis of a dermal fibroblast in primary culture from a control (a and b) and the subject with HGPS (c and d). Labelling was performed with anti-lamin A/C antibodies. Note the presence of irregularly shaped nuclear envelopes in many of the subject's fibroblasts
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Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene.
4001 16906 Ensembl ENSG00000113368 ENSMUSG00000024590 UniProt P20700 P14733 RefSeq (mRNA) NM_001198557 NM_005573 NM_010721 RefSeq (protein) NP_001185486 NP_005564 NP_034851 Location (UCSC) Chr 5: 126.78 – 126.84 Mb Chr 18: 56.84 – 56.89 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of ...
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Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene.