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In general, medical therapy is non-curative and is used for mild-to-moderate regurgitation or in patients unable to tolerate surgery. [15] In acute MR secondary to a mechanical defect in the heart (i.e., rupture of a papillary muscle or chordae tendineae), the treatment of choice is mitral valve surgery.
In The Framingham Heart Study presence of any severity of tricuspid regurgitation, ranging from trace to above moderate was in 82% of men and in 85.7% of women. [2] Mild tricuspid regurgitation tend to be common and benign and in structurally normal tricuspid valve apparatus can be considered a normal variant. [1]
Mitral valve prolapse is frequently associated with mild mitral regurgitation, [15] where blood aberrantly flows from the left ventricle into the left atrium during systole. In the United States , MVP is the most common cause of severe, non-ischemic mitral regurgitation. [ 4 ]
Mild to moderate aortic regurgitation should be followed with echocardiography and a cardiac stress test once every 1–2 years. [15] In severe moderate/severe cases, patients should be followed with echocardiography and cardiac stress test and/or isotope perfusion imaging every 3–6 months.
Mitral regurgitation is the most common form of mitral valve dysfunction. Today more than 2.5 million Americans are estimated to be affected by mitral regurgitation. This number is expected to double by the year 2030. Every year, 300,000 people worldwide undergo open heart surgery for mitral valve repair, 44,000 people in the US alone. [1]
Aortic regurgitation (AR), also known as aortic insufficiency (AI), is the leaking of the aortic valve of the heart that causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle. As a consequence, the cardiac muscle is forced to work harder than normal.
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