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An orexigenic, or appetite stimulant, is a drug, hormone, or compound that increases appetite and may induce hyperphagia. This can be a medication or a naturally occurring neuropeptide hormone, such as ghrelin , orexin or neuropeptide Y , [ 1 ] [ 2 ] which increases hunger and therefore enhances food consumption .
Appetite has a relationship with every individual's behavior. Appetitive behaviour also known as approach behaviour, and consummatory behaviour, are the only processes that involve energy intake, whereas all other behaviours affect the release of energy. When stressed, appetite levels may increase and result in an increase of food intake.
Knocking out vagal nerve receptors has been shown to cause hyperphagia. [4] Changes in hormones associated with the female menstrual cycle can lead to extreme hunger right before the period. Spikes in estrogen and progesterone and decreased serotonin can lead to cravings for carbohydrates and fats. [5] Polyphagia is found in the following ...
A large study published in Nature Medicine reviewed the effects of GLP-1 drugs like Ozempic and Mounjaro on 175 different health outcomes. The findings show benefits for brain and heart health ...
The 5-HT 2C receptors are the only G-protein coupled receptors known to undergo a post-transcriptional process of RNA editing. The 5-HT 2C receptor gene is found on the X-chromosome , Xq24. This gene product undergoes an RNA editing process leading to a decrease in agonist binding affinity, however antagonist binding remains unaltered.
Other mental health conditions, medications, and underlying medical issues can cause weight loss and changes in appetite. If you’ve noticed significant weight loss lately, it’s best to seek ...
A person may be underweight due to genetics, [7] [8] poor absorption of nutrients, increased metabolic rate or energy expenditure, lack of food (frequently due to poverty), low appetite, drugs that affect appetite, illness (physical or mental) or the eating disorder anorexia nervosa. [9] [10]
Changes in appetite or weight are common among antidepressants but are largely drug-dependent and related to which neurotransmitters they affect. Mirtazapine and paroxetine, for example, may be associated with weight gain and/or increased appetite, [178] [179] [180] while others (such as bupropion and venlafaxine) achieve the opposite effect ...