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  2. Pyruvate carboxylase deficiency - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_carboxylase...

    Pyruvate carboxylase deficiency is an inherited disorder that causes lactic acid to accumulate in the blood. [2] High levels of these substances can damage the body's organs and tissues, particularly in the nervous system. Pyruvate carboxylase deficiency is a rare condition, with an estimated incidence of 1 in 250,000 births worldwide.

  3. Sitosterolemia - Wikipedia

    en.wikipedia.org/wiki/Sitosterolemia

    Plasma sitosterol levels in sitosterolemia patients are 10–25 times higher than in unaffected individuals (8–60 mg/dl). Not all patients with sitosterolemia have tendon xanthomas, thus, the absence of this should not be used to exclude this diagnosis. [citation needed] Xanthomas may appear at any age, even in childhood.

  4. Pyruvate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_dehydrogenase...

    Symptoms Definition/Explanation Lactic Acidosis High levels of lactate in the blood; can cause nausea, vomiting, breathing problems, abnormal heartbeats *In less severe cases, signs of lactic acidosis can include ataxia and episodes may only occur when ill, under stress, or after consuming high amounts of carbohydrates. Hyperammonemia

  5. Hyperuricosuria - Wikipedia

    en.wikipedia.org/wiki/Hyperuricosuria

    Hyperuricosuria is a medical term referring to the presence of excessive amounts of uric acid in the urine. For men this is at a rate greater than 800 mg/day, and for women, 750 mg/day. [1] Notable direct causes of hyperuricosuria are dissolution of uric acid crystals in the kidneys or urinary bladder, and hyperuricemia.

  6. Pyruvate carboxylase - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_carboxylase

    The reaction it catalyzes is: pyruvate + HCO − 3 + ATP → oxaloacetate + ADP + P. It is an important anaplerotic reaction that creates oxaloacetate from pyruvate. PC contains a biotin prosthetic group [1] and is typically localized to the mitochondria in eukaryotes with exceptions to some fungal species such as Aspergillus nidulans which have a cytosolic PC.

  7. Pyruvic acid - Wikipedia

    en.wikipedia.org/wiki/Pyruvic_acid

    Jöns Jacob Berzelius characterized this other acid the following year and named pyruvic acid because it was distilled using heat. [5] [6] The correct molecular structure was deduced by the 1870s. [7] Pyruvic acid is a colorless liquid with a smell similar to that of acetic acid and is miscible with water. [8]

  8. The best skin care routine for your 60s, according to ... - AOL

    www.aol.com/lifestyle/best-skin-care-routine-for...

    Ingredients like retinoids, hyaluronic acid and niacinamide are important in a lot of ways. Dr. Kopelman says that niacinamide is good for protecting your skin's barrier and reducing inflammation ...

  9. Acute uric acid nephropathy - Wikipedia

    en.wikipedia.org/wiki/Acute_uric_acid_nephropathy

    Treatment is focused on preventing deposition of uric acid within the urinary system by increasing urine volume with potent diuretics such as furosemide. Raising the urinary pH to a level higher than 7 (alkalinization) is often difficult to attain, although sodium bicarbonate and/or acetazolamide are sometimes used in an attempt to increase ...