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Bethanechol is a parasympathomimetic choline carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. Unlike acetylcholine , bethanechol is not hydrolyzed by cholinesterase and will therefore have a long duration of action.
Bethanechol is a muscarinic agonist.It is included in the therapy for underactive bladder with poor contraction of detrusor muscle. [2] Since contraction of detrusor muscle in the bladder is controlled by the parasympathetic nervous system, Bethanechol can bind to muscarinic receptors to stimulate activation of the parasympathetic nervous system and restore contraction of detrusor muscle.
A parasympathomimetic drug, sometimes called a cholinomimetic drug [1] or cholinergic receptor stimulating agent, [2] is a substance that stimulates the parasympathetic nervous system (PSNS).
Comparison of cholinergic agonists [10]; Substance Receptor specificity Hydrolysis by acetylcholinesterase Comments Muscarinic Nicotinic Acetylcholine +++ +++ +++ Endogenous ligand
With strong bases such as sodium hydride or sodium they form salts [a] called alkoxides, with the general formula RO − M + (where R is an alkyl and M is a metal). R−OH + NaH → R−O − Na + + H 2 2 R−OH + 2 Na → 2 R−O − Na + + H 2. The acidity of alcohols is strongly affected by solvation. In the gas phase, alcohols are more ...
Drain cleaners usually contain a strong base such as sodium hydroxide that decomposes hair and converts fats into water-soluble products. The reaction is exothermic, releasing heat to soften the fats. Drain cleaners can also contain aluminum, which reacts with sodium hydroxide to produce bubbles of hydrogen gas that help to break up the clog. [11]