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In a disconnective procedure the neural connections in the brain that allow the seizures to spread are disconnected. In most cases epilepsy surgery is only an option when the area of the brain that causes the seizures - the so-called epileptic focus can be clearly identified and is not responsible for critical functions such as language.
First line therapy for epilepsy involves treatment with anticonvulsive drugs, also called antiepileptic drugs– most patients will respond to trials of one or two different medications. [5] The goal of treatment is the elimination of seizures, since uncontrolled seizures carry significant risks, including injury and sudden unexpected death in ...
Post-traumatic epilepsy (PTE) is a form of acquired epilepsy that results from brain damage caused by physical trauma to the brain (traumatic brain injury, abbreviated TBI). [1] A person with PTE experiences repeated post-traumatic seizures (PTS, seizures that result from TBI) more than a week after the initial injury. [ 2 ]
The vagus nerve stimulator is a device that can be implanted into patients with epilepsy, especially that which originates from a specific part of the brain. However, both of these treatment options can cause severe adverse effects. Additionally, while seizure frequency typically decreases, they often do not stop entirely. [40] [41]
Epilepsy is more common among children than adults, affecting about 6 out of 1000 US children that are between the age of 0 to 5 years old. [2] The epileptic seizures can be of different types depending on the part of the brain that was affected, seizures are classified in 2 main types partial seizure or generalized seizure. [1]
[38] [37] This is a possible mechanism for why there is hyper-excitability of neurons in seizures. Seizures that occur after brain injury may be due to the brain adapting to injury (neuroplasticity). [40] This process is known as epileptogenesis. [41] There is loss of inhibitory neurons because they die due to the injury.
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