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A comprehensive compendium of human long non-coding RNAs. [4] [5] lncRNAdb: The Reference Database For Functional Long Noncoding RNAs. [6] LncRNAWiki: A wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs) [7] LncBook
In 2005 the landscape of the mammalian genome was described as numerous 'foci' of transcription that are separated by long stretches of intergenic space. [9] While some long ncRNAs are located within the intergenic stretches, the majority are overlapping sense and antisense transcripts that often include protein-coding genes, [23] giving rise to a complex hierarchy of overlapping isoforms. [24]
In bioinformatics, lncRNAdb is a biological database of Long non-coding RNAs [1] [2] The database focuses on those RNAs which have been experimentally characterised with a biological function. The database currently holds over 290 lncRNAs from around 60 species. Example lncRNAs in the database are HOTAIR and Xist. [1] [2]
The transcriptome includes the transcripts of protein-coding genes (mRNA plus introns) as well as the transcripts of non-coding genes (functional RNAs plus introns). Ribosomal RNA/rRNA: Usually the most abundant RNA in the transcriptome. Long non-coding RNA/lncRNA: Non-coding RNA transcripts that are more than 200 nucleotides long. Members of ...
The roles of non-coding RNAs: Ribonucleoproteins are shown in red, non-coding RNAs in blue. A non-coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene.
How NORAD works with PUM proteins to contribute to genomic instability. [1]Noncoding RNA Activated by DNA Damage (NORAD) is a long non-coding RNA that responds to DNA damage and plays a significant role in preserving stability (keeping it accurate and unchanged) of genetic information within cells. [2]
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Endogenous RNA regulators, between 21 and 24 nt in length, and are generated from complementary mRNA transcripts which are further processed into siRNA: OxyS RNA: oxidative stress response RNA RF00035: Small non coding RNA which is induced in response to oxidative stress in Escherichia coli: piRNA: piwi-interacting RNA multiple families