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Transitional cell carcinoma is a type of cancer that arises from the transitional epithelium, a tissue lining the inner surface of these hollow organs. [1] It typically occurs in the urothelium of the urinary system ; in that case, it is also called urothelial carcinoma .
The TNM scores are combined to determine the cancer case's stage on a scale of 0 to 4 and a higher stage means a more extensive cancer with a poorer prognosis. [4] Around 75% of cases are confined to the bladder at the time of diagnosis (T scores: Tis, Ta, or T1), and are called non-muscle-invasive bladder cancer (NMIBC).
Micrograph of transitional cell carcinoma of the ovary. H&E stain . Transitional cell carcinoma of the ovary ( TCC of the ovary ) is a rare type of ovarian cancer that has an appearance similar to urothelial carcinoma (also known as transitional cell carcinoma).
Transitional cell carcinoma is the most common form of cancer in the lower urinary tract—the bladder and urethra. This video discusses the pathophysiology, signs and symptoms, diagnosis, and treatment of transitional cell carcinoma.
[2] [4] Transitional cell carcinoma is "a common cause of ureter cancer and other urinary (renal pelvic) tract cancers." [1] Because the inside of the ureters and the inside of the bladder contain the same cell type, people who have been diagnosed with ureteral cancer are more likely to also be diagnosed with bladder cancer, and vice versa. [3]
Histologically, they have dense fibrous stroma with areas of transitional epithelium and some squamous differentiation. To be classified as a malignant Brenner tumor, it must have Brenner tumor foci and transitional cell carcinoma. The transitional cell carcinoma component is typically poorly differentiated and resembles urinary tract cancer. [29]
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The following is a list of cancer types.Cancer is a group of diseases that involve abnormal increases in the number of cells, with the potential to invade or spread to other parts of the body. [1]