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It arises from the basilar artery on each side at the level of the junction between the medulla oblongata and the pons in the brainstem. It has a variable course, passing backward to be distributed to the anterior part of the undersurface of the cerebellum, anastomosing with both the posterior inferior cerebellar (PICA) branch of the vertebral ...
A disrupted blood supply to posterior inferior cerebellar artery due to a thrombus or embolus can result in a stroke and lead to lateral medullary syndrome. Severe occlusion of this artery or to vertebral arteries could lead to Horner's Syndrome as well.
The circle of Willis (also called Willis' circle, loop of Willis, cerebral arterial circle, and Willis polygon) is a circulatory anastomosis that supplies blood to the brain and surrounding structures in reptiles, birds and mammals, including humans. [1] It is named after Thomas Willis (1621–1675), an English physician. [2]
In general, decrease in blood flow to the brain can be a result of thrombosis causing a partial or full blockage of blood vessels, hypotension in systemic circulation (and consequently the brain), or cardiac arrest. This decrease in blood flow in the cerebral vascular system can result in a buildup of metabolic wastes generated by neurons and ...
Leptomeningeal collateral vessels from the anterior cerebral artery and posterior cerebral artery appeared to allow for perfusion of some brain tissue to persist, partially compensating for the loss of the major vessel. [6] This compensatory effect is however usually inadequate to maintain a normal blood supply. [11]
The cerebral arteries describe three main pairs of arteries and their branches, which perfuse the cerebrum of the brain. The three main arteries are the: Anterior cerebral artery (ACA), which supplies blood to the medial portion of the brain, including the superior parts of the frontal and anterior parietal lobes [1]
Ischemia is the loss of blood flow to the focal region of the brain. This produces heterogeneous areas of ischemia at the affected vascular region, furthermore, blood flow is limited to a residual flow. Regions with blood flow of less than 10 mL/100 g of tissue/min are core regions (cells here die within minutes of a stroke). The ischemic ...
Blood resistance varies depending on blood viscosity and its plugged flow (or sheath flow since they are complementary across the vessel section) size as well, and on the size of the vessels. Assuming steady, laminar flow in the vessel, the blood vessels behavior is similar to that of a pipe.