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Individual jurisdictions have adopted varied testing protocols, including whom to test, how often to test, analysis protocols, sample collection and the uses of test results. [ 6 ] [ 7 ] [ 8 ] This variation has likely significantly impacted reported statistics, including case and test numbers, case fatality rates and case demographics.
Results from studies are combined using different approaches. One approach frequently used in meta-analysis in health care research is termed 'inverse variance method'. The average effect size across all studies is computed as a weighted mean, whereby the weights are equal to the inverse variance of each study's effect estimator. Larger studies ...