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In hematology, thrombocytopenia is a condition characterized by abnormally low levels of platelets (also known as thrombocytes) in the blood. [2] Low levels of platelets in turn may lead to prolonged or excessive bleeding.
Clinical data show that many patients with serious bacterial or viral infections have thrombocytopenia, thus reducing their contribution to inflammation. Platelet-leukocyte aggregates (PLAs) found in circulation are typical in sepsis or inflammatory bowel disease , showing the connection between thrombocytes and immune cells.
Giant platelet disorders, also known as macrothrombocytopenia, are rare disorders featuring abnormally large platelets, thrombocytopenia and a tendency to bleeding. Giant platelets cannot stick adequately to injured blood vessel walls, resulting in abnormal bleeding when injured.
Thrombosis (from Ancient Greek θρόμβωσις (thrómbōsis) ' clotting ') is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.
Sampling bias is usually classified as a subtype of selection bias, [7] sometimes specifically termed sample selection bias, [8] [9] [10] but some classify it as a separate type of bias. [11]
In the theory of finite population sampling, Bernoulli sampling is a sampling process where each element of the population is subjected to an independent Bernoulli trial which determines whether the element becomes part of the sample.