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The intestinal epithelium is the single cell layer that forms the luminal surface (lining) of both the small and large intestine (colon) of the gastrointestinal tract. Composed of simple columnar epithelium its main functions are absorption, and secretion. Useful substances are absorbed into the body, and the entry of harmful substances is ...
The appendix has a mucosa resembling the colon but is heavily infiltrated with lymphocytes. Transition between the different types of epithelium occurs at the junction between the oesophagus and stomach ; between the stomach and duodenum , between the ileum and caecum , and at the pectinate line of the anus .
The medications used to induce and maintain a remission somewhat overlap, but the treatments are different. Physicians first direct treatment to inducing remission, which involves relief of symptoms and mucosal healing of the colon's lining, and then longer-term treatment to maintain remission and prevent complications. [92]
Physicians first direct treatment to inducing a remission which involves relief of symptoms and mucosal healing of the lining of the colon and then longer-term treatment to maintain the remission. Anaemia , caused by both chronic blood loss from the gastrointestinal tract and reduced absorption due to the up-regulation of hepcidin should also ...
The intestinal mucosal barrier, also referred to as intestinal barrier, refers to the property of the intestinal mucosa that ensures adequate containment of undesirable luminal contents within the intestine while preserving the ability to absorb nutrients. The separation it provides between the body and the gut prevents the uncontrolled ...
The trapped section of bowel may have its blood supply cut off, which causes ischemia (lack of oxygen in the tissues). The mucosa (gut lining) is very sensitive to ischemia, and responds by sloughing off into the gut. This creates the classically described "red currant jelly" stool, which is a mixture of sloughed mucosa, blood, and mucus. [7]
Due to the disruption of digestive processes by the overgrowth of intestinal bacteria; malabsorption of bile salts, fat and fat-soluble vitamins, protein and carbohydrates results in damage to the mucosal lining of the intestine by bacteria or via the production of toxic metabolites.
Denudation coupled with peeling and cracking of skin gives rise to a "crazy pavement dermatosis" pattern seen in Kwashiorkor or Kwashiorkor-Marasmus complex. In occupational asthma, the denudation of the bronchial mucosa can occur in the setting of nonimmunologic exposures (i.e., chemical spill, chlorine, ammonia), causing irritation.