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  2. Viloxazine - Wikipedia

    en.wikipedia.org/wiki/Viloxazine

    [6] [1] [5] The immediate-release form has an elimination half-life of 2.5 hours [6] [2] while the half-life of the extended-release form is 7 hours. [1] Viloxazine was first described by 1972 [10] and was marketed as an antidepressant in Europe in 1974. [6] [11] It was not marketed in the United States at this time. [12]

  3. Sofosbuvir/velpatasvir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir/velpatasvir

    Sofosbuvir/velpatasvir, sold under the brand name Epclusa among others, is a fixed-dose combination medication for the treatment of hepatitis C in adults. [2] [5] [6] [7] It combines sofosbuvir and velpatasvir. [2] [5] [6] It is more than 90% effective for hepatitis C genotypes one through six. [2]

  4. List of investigational attention deficit hyperactivity ...

    en.wikipedia.org/wiki/List_of_investigational...

    This is a list of investigational attention deficit hyperactivity disorder drugs, or drugs that are currently under development for clinical use in the treatment of attention deficit hyperactivity disorder (ADHD) but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in ...

  5. Liquidia's inhaled drug fails to get traditional approval in ...

    www.aol.com/news/us-fda-grants-tentative...

    (Reuters) -The U.S. Food and Drug Administration on Monday delayed traditional approval for Liquidia Corp's inhaled drug for types of lung disorders, and allowed only tentative clearances, sending ...

  6. Management of attention deficit hyperactivity disorder

    en.wikipedia.org/wiki/Management_of_attention...

    Attention deficit hyperactivity disorder management options are evidence-based practices with established treatment efficacy for ADHD.Approaches that have been evaluated in the management of ADHD symptoms include FDA-approved pharmacologic treatment and other pharmaceutical agents, psychological or behavioral approaches, combined pharmacological and behavioral approaches, cognitive training ...

  7. Esaxerenone - Wikipedia

    en.wikipedia.org/wiki/Esaxerenone

    Daiichi Sankyo Company, Limited on January 8, 2019 announced the receipt of marketing approval in Japan for MINNEBROTM Tablets 1.25 mg, 2.5 mg and 5 mg (generic name: esaxerenone) for the treatment of hypertension. As of January 2019, esaxerenone is in phase III clinical trials for diabetic nephropathies. [1] [4]

  8. US FDA approves Verona Pharma's inhaled COPD therapy - AOL

    www.aol.com/news/us-fda-approves-verona-pharmas...

    The add-on COPD drug market is seeing interest from larger drugmakers as well, especially Regeneron and Sanofi's blockbuster anti-inflammatory drug Dupixent, although the FDA extended its review ...

  9. Clofarabine - Wikipedia

    en.wikipedia.org/wiki/Clofarabine

    Clofarabine-5´-triphosphate is the active-metabolite, and it inhibits ribonucleotide reductase, resulting in a decrease cellular dNTP concentrations, which promotes greater incorporation of clofarabine-5´-triphosphate during DNA synthesis. Embedded clofarabine-5´-monophosphate in the DNA promotes polymerase arrest at the replication fork ...

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