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M. tuberculosis is able to reproduce inside the macrophage and will eventually kill the immune cell. The primary site of infection in the lungs, known as the Ghon focus, is generally located in either the upper part of the lower lobe, or the lower part of the upper lobe. [13] Tuberculosis of the lungs may also occur via infection from the blood ...
Since 2018, all members of this species complex are considered synonyms of M. tuberculosis as far as bacterial nomenclature is concerned. The IJSEM article reports that M. africanum, M. bovis, M. caprae, M. pinnipedii are 99.21–99.92% identical to M. tuberculosis on the whole-genome level, failing the criteria to be considered independent ...
Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB. The medical standard for active TB is a short course treatment involving a combination of isoniazid , rifampicin (also known as Rifampin), pyrazinamide , and ethambutol for the first two months.
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
The resurgence of tuberculosis in the United States, the advent of HIV-related tuberculosis, and the development of strains of TB resistant to the first-line therapies developed in recent decades serve to reinforce the thesis that Mycobacterium tuberculosis, the causative organism, makes its own preferential option for the poor. [66]
The Pertanika Journal of Social Sciences & Humanities is a quarterly peer-reviewed open-access academic journal published by UPM Press (University of Putra Malaysia). It covers all aspects of social and behavioural sciences as well as the humanities. The editor-in-chief is Roziah Mohd Rasdi (Universiti of Putra Malaysia).
Thomas McKeown (1912–1988) was a British physician, epidemiologist and historian of medicine. [1] [2] Largely based on demographic data from England and Wales, McKeown argued that the population growth since the late eighteenth century was due to improving economic conditions, i.e. better nutrition, rather than to better hygiene, public health measures, and improved medicine.
In 2007, the prevalence of TB per 100,000 people was relatively high in Asia, and was highest in sub-Saharan Africa. [3] [1] In China, tuberculosis has been the number 1 cause of death from infectious disease in adults. In 1990, 360,000 people in China died from tuberculosis. Tuberculosis is one of China's major public health problems.