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A branded version called Cortrosyn, which was created and developed by Organon and was approved by the FDA in 1970, and as of January 2017 was under the control of Amphastar Pharmaceuticals, [24] [25] and there were three generic versions under ANDAs, one for Mylan approved in 2009, [26] one for Sandoz/Novartis, approved in 2012, [27] and ...
The ACTH test (also called the cosyntropin, tetracosactide, or Synacthen test) is a medical test usually requested and interpreted by endocrinologists to assess the functioning of the adrenal glands' stress response by measuring the adrenal response to adrenocorticotropic hormone (ACTH; corticotropin) or another corticotropic agent such as tetracosactide (cosyntropin, tetracosactrin; Synacthen ...
The specific activity of highly purified human enzyme is 890,000 units/mg, [5] meanwhile the enzyme activity produced by recombinant DNA technology is approximately 40 units/mg. [6] A typical dose is 2.5U/kg every two weeks, up to a maximum of 60 U/kg once every two weeks, and safety has been established from ages 2 and up. [7]
A late effect can be caused directly by the earlier condition, or indirectly by the treatment for the earlier condition. Some late effects can occur decades later. Historically, late effects have been very difficult to connect with their causes, but as survival and life span have increased and "follow up" has become standard practice, these ...
In the "study" phase, the participant is given a list of words or other items to be remembered, presented one at a time. The participant may be told to try to remember these items for later ("intentional" encoding), or may be asked to make judgments about the item without realizing that there will later be a memory test for the items ...
Overall, according to a study in British Columbia, approximately 2.3 children per 100,000 births (1 in 43,000) have some form of glycogen storage disease. [103] In the United States, they are estimated to occur in 1 per 20,000–25,000 births. [10] Dutch incidence rate is estimated to be 1 per 40,000 births.
After thawing, single units of cryo (or units pooled using a sterile method) can be stored at 20–24 °C for up to 6 hours. If units of cryo are pooled in an open system, they can only be held at 20–24 °C for up to 4 hours. [3] Presently cryo cannot be re-frozen for storage after it is thawed for use if it is not transfused.
Glycogen storage disease type V (GSD5, GSD-V), [1] also known as McArdle's disease, [2] is a metabolic disorder, one of the metabolic myopathies, more specifically a muscle glycogen storage disease, caused by a deficiency of myophosphorylase. [3] [4] Its incidence is reported as one in 100,000, roughly the same as glycogen storage disease type ...