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  2. Prazosin - Wikipedia

    en.wikipedia.org/wiki/Prazosin

    Prazosin, sold under the brand name Minipress among others, is a medication used to treat high blood pressure, symptoms of an enlarged prostate, and nightmares related to post-traumatic stress disorder (PTSD). [6] It is an α 1 blocker. [6] It is a less preferred treatment of high blood pressure. [6] Other uses may include heart failure and ...

  3. List of drugs known for off-label use - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_known_for...

    Prazosin (Minipress) for nightmares: prazosin is approved for the use of hypertension. A 2012 systematic review showed a small benefit for the treatment of PTSD-associated night terrors. Other non-FDA-approved uses for prazosin include the treatment of Raynaud's disease and poisoning due to scorpion venom.

  4. Alpha-1 blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_blocker

    Prazosin is commonly used as an antihypertensive, but because alpha-1-adrenergic activity has been connected to fear and startle responses, it sees use as a PTSD treatment. [19] [20] Prazosin has been established as an effective and safe centrally active alpha-1-adrenergic receptor antagonist. It can be used to treat trauma-related nightmares ...

  5. Nightmare - Wikipedia

    en.wikipedia.org/wiki/Nightmare

    Prazosin (alpha-1 blocker) appears useful in decreasing the number of nightmares and the distress caused by them in people with PTSD. [28] [29] Risperidone (atypical antipsychotic) at a dosage of 2 mg per day, has been shown in a case report to lead to the remission of nightmares on the first night. [29]

  6. 20 details you probably missed in 'The Nightmare Before ... - AOL

    www.aol.com/20-details-probably-missed-nightmare...

    18 things you didn't know about 'The Nightmare Before Christmas' Every Halloween-themed Disney Channel original movie, ranked by audiences 14 of the best Halloween movies that aren't too scary

  7. Alpha blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha_blocker

    High doses of the α 1 blocker, prazosin, have been efficacious in treating patients with PTSD induced nightmares due to its ability to block the effects of norepinephrine. [27] Adverse effects of prazosin to treat PTSD nightmares include dizziness, first dose effect (a sudden loss of consciousness), weakness, nausea, and fatigue. [27]

  8. Anxiety mounts over worker buyout plan as judge hits pause - AOL

    www.aol.com/news/anxiety-mounts-u-government...

    The future of millions of federal workers was plunged into another day of chaos Thursday as they faced fresh uncertainty over an unprecedented program pushing financial incentives in exchange for ...

  9. Nightmare disorder - Wikipedia

    en.wikipedia.org/wiki/Nightmare_disorder

    Prazosin would significantly decrease the number of PTSD related nightmares and would therefore improve sleep quality. [12] However, only few studies considered the effect of Prazosin in idiopathic nightmares. [12] Benzodiazepines are also often used to treat nightmare disorder, despite the lack of efficacy demonstrated in empirical studies. [12]