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  2. Dutasteride - Wikipedia

    en.wikipedia.org/wiki/Dutasteride

    Dutasteride is sometimes used as a component of hormone therapy for transgender women in combination with an estrogen and/or another antiandrogen such as spironolactone. [7] It may be useful for preventing and treating scalp hair loss and can also be used as a general antiandrogen for in those who have issues tolerating spironolactone, though as a α-reductase inhibitor it has limited effects ...

  3. 5α-Reductase inhibitor - Wikipedia

    en.wikipedia.org/wiki/5α-reductase_inhibitor

    Dutasteride (brand name Avodart) inhibits all three 5α-reductase isoenzymes and can decrease DHT levels by 95%. [9] [10] It can also reduce DHT levels in the prostate by 97 to 99% in men with prostate cancer. [11] [12] Epristeride (brand names Aipuliete, Chuanliu) is marketed in China for the treatment of benign prostatic hyperplasia.

  4. Discovery and development of 5α-reductase inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Dutasteride (Avodart) was the second steroidal 5α-reductase approved after finasteride. It is a competitive inhibitor of all three 5α-reductase isoenzymes [ 4 ] and it inhibits types 1 and 2 better than finasteride, leading to it causing further reduction in DHT, with >90% reduced DHT levels following 1 year of oral administration.

  5. List of GSK plc products - Wikipedia

    en.wikipedia.org/wiki/List_of_GSK_plc_products

    Avodart (dutasteride) Bactroban (mupirocin) Becotide (beclomethasone dipropionate) Benlysta (belimumab) Betnovate (betamethasone valerate) Blenrep (belantamab mafodotin) Breo (fluticasone furoate, vilanterol) Ceftin (cefuroxime axetil) Combodart (dutasteride / tamsulosin hydrochloride) Cutivate (fluticasone propionate) Daraprim (pyrimethamine ...

  6. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    Therapeutic, diagnostic and preventive monoclonal antibodies are clones of a single parent cell. When used as drugs, the International Nonproprietary Names (INNs) end in -mab.

  7. FDA approves new type of non-opioid pain medication, 1st of ...

    www.aol.com/news/fda-approves-type-non-opioid...

    The U.S. Food and Drug Administration (FDA) on Thursday approved a new type of prescription pain medication for adults to treat moderate to severe acute pain. The drug, called Journavx ...

  8. FDA approves new pain medication as an alternative to ... - AOL

    www.aol.com/fda-approves-pain-medication...

    The FDA on Thursday approved a new class of pain medication that provides an alternative to opioids. It will be sold under the brand name Journavx.

  9. List of 5α-reductase inhibitors - Wikipedia

    en.wikipedia.org/wiki/List_of_5α-reductase...

    This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...