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Thrush, a common condition caused by overgrowth of the fungus Candida albicans. Cases are characterized by growth of matted, yellow-white patches of fungus in the mouth. Oral microbiology is the study of the microorganisms (microbiota) of the oral cavity and their interactions between oral microorganisms or with the host. [1]
Subgingival biofilm is plaque that is located under the gums. It occurs after the formation of the supragingival biofilm by a downward growth of the bacteria from above the gums to below. This plaque is mostly made up of anaerobic bacteria, meaning that these bacteria will only survive if there is no oxygen.
While S. mutans grows in the biofilm, cells maintain a balance of metabolism that involves production and detoxification. Biofilm is an aggregate of microorganisms in which cells adhere to each other or a surface. Bacteria in the biofilm community can actually generate various toxic compounds that interfere with the growth of other competing ...
Given the natural history of a mouth infection, the vast majority of clinically-treated oral infections are polymicrobial, or caused by multiple different species of bacteria at the same time. [9] Until the source of the infection is controlled with some form of drainage and antibiotics, a mouth infection will likely not resolve on its own.
Bacterial toxins and the body's natural defenses start to break down the bone and connective tissues. The tooth may eventually become loose and have to be removed. Scarlet fever is caused by a particular streptococci species, Streptococci Pyogenes , and is classified be a severe form of bacterial sore throat.
Oral fungal infections are most commonly caused by different Candida species such as Candida albicans, Candida glabrata and Candida tropicalis resulting in oral candidiasis. [18] [21] There are several predisposing factors to fungal infections such as systemic disease for example Diabetes, recent antibiotics, use of steroid inhalers etc ...
On the tongue, there is loss of the lingual papillae (depapillation), leaving a smooth area. [5] Acute erythematous candidiasis usually occurs on the dorsum of the tongue in persons taking long term corticosteroids or antibiotics, but occasionally it can occur after only a few days of using a topical antibiotic. [9]
Other than chemicals, enzymes have been used to degrade the biofilm matrix and eject biofilm cells forcibly. First shown in P. aeruginosa, a glycosyl hydrolase PslG can trigger biofilm disassembly by disrupting exopolysaccharide matrix in biofilms effectively and can be used in combination with antibiotics to kill the cells released from biofilms.