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Malignant rhabdoid tumour (MRT) is a very aggressive form of tumour originally described as a variant of Wilms' tumour, which is primarily a kidney tumour that occurs mainly in children. MRT was first described as a variant of Wilms' tumour of the kidney in 1978. [1] MRTs are a rare and highly malignant childhood neoplasm.
It predisposes individuals to renal cell cancer, an association denominated hereditary leiomyomatosis and renal cell cancer. [1] [2] It is also associated with increased risk of uterine leiomyosarcoma. [3] The syndrome is caused by a mutation in the fumarate hydratase gene, which leads to an accumulation of fumarate.
Kidney cancer, also known as renal cancer, is a group of cancers that starts in the kidney. [4] Symptoms may include blood in the urine, a lump in the abdomen, or back pain. [1] [2] [3] Fever, weight loss, and tiredness may also occur. [1] [2] [3] Complications can include spread to the lungs or brain. [6]
Trousseau's syndrome is a rare variant of venous thrombosis that is characterized by recurrent, migratory thrombosis in superficial veins and in uncommon sites, such as the chest wall and arms. This syndrome is particularly associated with pancreatic, gastric and lung cancer and Trousseau's syndrome can be an early sign of cancer [ 2 ] [ 3 ...
Desmoplastic small-round-cell tumor (DSRCT) is an aggressive and rare cancer that primarily occurs as masses in the abdomen. [4] Other areas affected may include the lymph nodes, the lining of the abdomen, diaphragm, spleen, liver, chest wall, skull, spinal cord, large intestine, small intestine, bladder, brain, lungs, testicles, ovaries, and the pelvis.
Papillary renal cell carcinoma (PRCC) is a malignant, heterogeneous tumor originating from renal tubular epithelial cells of the kidney, which comprises approximately 10-15% of all kidney neoplasms. [1] Based on its morphological features, PRCC can be classified into two main subtypes, which are type 1 and type 2 (eosinophilic). [2]
The most frequent, malignant, primary kidney cancer is renal cell carcinoma (RCC) - which has several subtypes: Clear cell RCC, an epithelial cell tumour of the kidney that accounts for 65-70% of all RCCs. [5] Papillary RCC, a renal tumour that accounts for 10-15% of all RCCs. Males are 1.5 times as likely to develop this type of tumour than ...
Small-cell lung carcinoma (SCLC) has long been divided into two clinicopathological stages, termed limited stage (LS) and extensive stage (ES). [8] The stage is generally determined by the presence or absence of metastases, whether or not the tumor appears limited to the thorax, and whether or not the entire tumor burden within the chest can feasibly be encompassed within a single radiotherapy ...
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