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Leptomeningeal carcinomatosis occurs when the cancer cells invade the cerebrospinal fluid [5] and spread throughout the central nervous system. [6] The metastatic tumor cells grow either attached to the pia mater covering the brain and spinal cord or floating unattached to the subarachnoid space . [ 7 ]
The lining of the abdominal cavity is a common site for surface dissemination. Ovarian carcinomas are common. Fluid produced by the cells can produce ascites which is typical in carcinomatosis, but less common in peritoneal sarcomatosis. [1]
Plus Therapeutics is developing nanoliposome-encapsulated BMEDA-chelated radioisotope drugs to treat various types of cancer. Rhenium (186Re) Obisbemeda is a Rhenium-186 radiolabeled therapeutic targeting recurrent glioblastoma, leptomeningeal metastases, and pediatric brain cancers.
Paclitaxel trevatide (development codes NG1005 and GRN1005) is an experimental chemotherapy drug that is under development by Angiochem Inc, a Canadian biotech company.. Phase II clinical trials have completed for several indications, and the company is preparing for phase III t
And while bacterial meningitis can be life-threatening, "early treatment improves outcomes," says Nagata. "The best treatments start with a prompt diagnosis of what is causing the disease," echoes ...
A Memorial Sloan Kettering phase 1 clinical trial revealed an immune response in some pancreatic cancer patients. Study co-author Dr. Vinod Balachandran talks about the impact on future cancer care.
"Addressing the role of obesity in endometrial cancer risk, prevention, and treatment." Journal of Clinical Oncology. " Cancer and Mediterranean diet : A review.
Therapies that attempt to optimize leptomeningeal collateral circulation appear to improve outcomes following acute ischaemic stroke. [2] MRI and CT brain imaging is used to determine the severity of a stroke, and help guide treatment. Fluid attenuated inversion recovery (FLAIR) vascular hyperintensity (FVH) is a radiographic marker seen on ...