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The world of depression treatment options is vast, varied and confusing at times. So many antidepressant medications, so many types of therapy, so many acronyms and so much information.
The Sequenced Treatment Alternatives to Relieve Depression Study (STAR*D) Trial [13] also found that patients had low response rates to alternative compounds after the failure of the first antidepressant. [2] [14] Thus, a need for more rapid, yet prolonged, efficacy in treatment has stimulated further research on alternative treatment options.
Sequenced Treatment Alternatives to Relieve Depression (STAR*D) was a collaborative study on the treatment of depression, funded by the National Institute of Mental Health. Its main focus was on the treatment of depression in patients where the first prescribed antidepressant proved inadequate.
In the study, 336 adults with treatment-resistant depression were randomly assigned to receive nasal esketamine in addition to the antidepressant medication they were already taking, either a ...
Medications for Depression: An Overview. Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used ...
Ketamine has been tested as a rapid-acting antidepressant [22] for treatment-resistant depression in bipolar disorder, and major depressive disorder. [23] Spravato, a nasal spray form of esketamine, was approved by the FDA in 2019 for use in treatment-resistant depression when combined with an oral antidepressant. [24] [25]
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