Search results
Results From The WOW.Com Content Network
Leukodystrophy is characterized by specific symptoms, including decreased motor function, muscle rigidity, and eventual degeneration of sight and hearing. While the disease is fatal, the age of onset is a key factor, as infants have a typical life expectancy of 2–8 years, while adults typically live more than a decade after onset.
Later onset of symptoms is associated with longer life expectancy, with older children generally surviving two to seven years after the initial diagnosis. [22] Krabbe disease occurs in about one in 100,000 births. [23] Because the disease is genetic, incidence rates vary widely from population to population. [21]
Autosomal dominant leukodystrophy with autonomic disease is a rare neurological condition of genetic origin which is ... the life expectancy can't be improved easily ...
Alexander disease is a very rare autosomal dominant leukodystrophy, which are neurological conditions caused by anomalies in the myelin which protects nerve fibers in the brain. The most common type is the infantile form that usually begins during the first two years of life.
The disease is one in a group of genetic disorders collectively known as leukodystrophies that affect the growth of the myelin sheath, the fatty covering—which acts as an insulator—on nerve fibers in the central nervous system. The several forms of Pelizaeus–Merzbacher disease include classic, congenital, transitional, and adult variants. [5]
Canavan disease typically results in death or development of life-threatening conditions by the age of ten, though life expectancy is variable, [14] and is highly dependent on specific circumstances. [15] On the other hand, the milder variants of the disorder seem not to have any effect on lifespan. [6]
Life expectancy may be plateauing. ... prevent up to 900,000 infants from having low birth weight and result in 1,500 fewer premature deaths a year from heart disease.
Leukoencephalopathy with vanishing white matter (VWM disease) is an autosomal recessive neurological disease. The cause of the disease are mutations in any of the 5 genes encoding subunits of the translation initiation factor eIF2B: EIF2B1, EIF2B2, EIF2B3, EIF2B4, or EIF2B5. The disease belongs to a family of conditions called the Leukodystrophies.