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Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. [9] It is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C 21 H 30 O 2 ) describes multiple isomers , [ 10 ] the term THC usually refers to the delta-9-THC isomer with ...
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Tetrahydrocannabinol (THC) is the primary psychoactive component of the Cannabis plant. Delta-9-tetrahydrocannabinol (Δ 9-THC, THC) and delta-8-tetrahydrocannabinol (Δ 8-THC), through intracellular CB 1 activation, induce anandamide and 2-arachidonoylglycerol synthesis produced naturally in the body and brain [citation needed] [dubious ...
[14] [15] Studies of chronic cannabis users have demonstrated, although inconsistently, a long-lasting effect on the attention span, memory function, and cognitive abilities of moderate-dose, long-term users. Once cannabis use is discontinued for several months, these effects disappear, unless the user started consuming during adolescence.
11-Hydroxy-Δ 9-tetrahydrocannabinol (11-OH-Δ 9-THC, alternatively numbered as 7-OH-Δ 1-THC), usually referred to as 11-hydroxy-THC is the main active metabolite of tetrahydrocannabinol (THC), which is formed in the body after Δ 9-THC is consumed.
It is an isomer of delta-9-tetrahydrocannabinol (delta-9-THC, Δ 9-THC), the compound commonly known as THC, with which it co-occurs in hemp; natural quantities of ∆ 8-THC found in hemp are low. Psychoactive effects are similar to that of Δ 9-THC, with central effects occurring by binding to cannabinoid receptors found in various regions of ...
Tetrahydrocannabinolic acid (THCA, 2-COOH-THC; conjugate base tetrahydrocannabinolate) is a precursor of tetrahydrocannabinol (THC), an active component of cannabis. [1]THCA is found in variable quantities in fresh, undried cannabis, but is progressively decarboxylated to THC with drying, and especially under intense heating such as when cannabis is smoked or cooked into cannabis edibles.
Reported neuroprotective effects (synergistic if coadministered with other cannabinoids) [15] Relevance to pain, itch, and inflammation via TRP channel activity [15] Tetrahydrocannabinol (THC) / Delta-9-Tetrahydrocannabinol (Δ 9-THC) Agonist at CB1 and CB2, as well as GPR55, GPR18, PPARγ, and TRPA1 [13] [16] Antagonist at TRPM8 [13] [16] and ...