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Cannabis use disorder (CUD), also known as cannabis addiction or marijuana addiction, is a psychiatric disorder defined in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders and ICD-10 as the continued use of cannabis despite clinically significant impairment.
New research published in The Lancet details an association between high cannabis potency — or concentration of tetrahydrocannabinol (THC) — and an increased risk of psychosis and cannabis use ...
Cannabis use disorder is defined in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders as a condition requiring treatment. [107] Several drugs have been investigated in an attempt to ameliorate the symptoms of stopping cannabis use. Such drugs include bupropion, divalproex, nefazodone, lofexidine, and dronabinol.
Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. [9] It is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C 21 H 30 O 2 ) describes multiple isomers , [ 10 ] the term THC usually refers to the delta-9-THC isomer with ...
A 2021 study found cannabis use disorder rose from 17.7% before marijuana was legalized in Canada to 24.3% after legalization. “As cannabis becomes increasingly legal and available, it’s ...
Friends who use can influence one another to take drugs that are more rewarding and have a higher potential for abuse. [63] Large-scale longitudinal studies in the UK and New Zealand from 2015 and 2017 showed an association between cannabis use and an increased probability of later disorders in the use of other drugs. [64] [65] [66]
The psychoactive component of cannabis, tetrahydrocannabinol (THC) is not effective in treating emotion-regulation and anxiety-related symptoms. [20] Conversely, THC has been empirically related to an increase anxiety symptoms through impacts on neurological areas impacting serotonin, noradrenalin, GABA and glutamate.
According to DSM-V criteria, 9% of those who are exposed to cannabis develop cannabis use disorder, compared to 20% for cocaine, 23% for alcohol and 68% for nicotine. Cannabis use disorder in the DSM-V involves a combination of DSM-IV criteria for cannabis abuse and dependence, plus the addition of craving, without the criterion related to ...