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Geriatric: Plasma concentrations of atorvastatin in healthy elderly subjects are higher than those in young adults. [3] However, clinical data suggests there is a similar reduction of LDL cholesterol and cardiovascular events at any dose in this population and adults younger than 65 years of age.
They recommended selective use of low-to-moderate doses statins in the same adults who have a calculated 10-year cardiovascular disease event risk of 7.5–10% or greater. [22] In people over the age of 70, statins decrease the risk of cardiovascular disease but only in those with a history of heavy cholesterol blockage in their arteries.
With the recent elucidation of the structures of the catalytic portion of human HMGR enzyme complexed with six different statins by a series of crystallography studies, new possibilities have opened up for the rational design and optimization of even better HGMR inhibitors.
A Novo Nordisk-funded 2021 study looked at almost 2,000 adults with excess body weight or obesity without diabetes. Participants took once-weekly 2.4-milligram (mg) semaglutide injections or a ...
Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia).
In adults and children age 2 and older, use it only on the neck and chest to ease coughing during a cold, per the Mayo Clinic. Vicks VapoRub is made of ingredients such as camphor, eucalyptus oil ...
No one ever wants to look back in regret. But for many retirees, that’s the reality. Not to be a downer at this fresh start time of year, but it’s useful to hear retirees’ regrets ...
The effects of rosuvastatin on low-density lipoprotein (LDL) cholesterol are dose-related. Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin.