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Wuchereria bancrofti is a filarial (arthropod-borne) nematode (roundworm) that is the major cause of lymphatic filariasis. It is one of the three parasitic worms, together with Brugia malayi and B. timori , that infect the lymphatic system to cause lymphatic filariasis.
Wuchereria bancrofti (Wb) belonging to the family Onchocercidae, accounts for more than 90% of the filarial infections worldwide. It completes its life cycle across two hosts, humans being the definitive host while the mosquitoes act as the intermediate host.
Lymphatic filariasis is a human disease caused by parasitic worms known as filarial worms. [2] [3] Usually acquired in childhood, it is a leading cause of permanent disability worldwide, impacting over a hundred million people and manifesting itself in a variety of severe clinical pathologies [6] [7] While most cases have no symptoms, some people develop a syndrome called elephantiasis, which ...
Wuchereria bancrofti [7] Three other medically important parasitic species are: Loa loa causes Loa loa filariasis also known as Calabar swelling; Mansonella streptocerca, which causes streptocerciasis, an itchy condition that creates depigmented skin lesions sometimes mistaken for the first signs of leprosy.
Buckley proposed to divide the old genus Wuchereria, into two genera, Wuchereria and introduced a new Brugia after the original discoverer. Then Wuchereria contains only W. bancrofti, which so far has been found to infect only humans, and the genus Brugia contains B. malayi, which infects humans and animals, as well as other zoonotic species. [12]
Wuchereria is a genus of nematodes belonging to the family Onchocercidae. [1] The species of this genus are found in Europe, Northern America, Africa. [1] Species: Wuchereria bancrofti (Cobbold, 1877) Wuchereria kalimantani Palmieri, Purnomo, Dennis & Marwoto, 1980.
Life cycle of Wuchereria bancrofti. After Bancroft's return from his travels, he carried on a large practice and, in addition to his scientific research on medical problems, developed his interest in economic botany.
The life cycle of Brugia timori is very similar to that of Wuchereria bancrofti and Brugia malayi, leading to nocturnal periodicity of the disease symptoms. Eosinophilia is common during acute stages of infection. [citation needed]