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Oral candidiasis (Acute pseudomembranous candidiasis), which is also known as oral thrush, among other names, [1] is candidiasis that occurs in the mouth. That is, oral candidiasis is a mycosis (yeast/fungal infection) of Candida species on the mucous membranes of the mouth.
Candidiasis is a fungal infection due to any species of the genus Candida (a yeast). [4] When it affects the mouth, in some countries it is commonly called thrush. [3] Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. [3]
The complications that arise from mouth infections depend on how long the infection has persisted and where the infection has spread. The three main, albeit rare, complications of mouth infections are osteomyelitis, cavernous sinus thrombosis, and deep neck space infections. [4]
Inflammatory papillary hyperplasia is commonly associated with Candida infection. [14] Strong correlation between denture stomatitis and poor hygiene in the use of prostheses have been found in a few studies in Brazil. [15] [16] Denture stomatitis is the most frequent denture related mucosal lesion and is always associated with Candida albicans.
Candida albicans is an opportunistic pathogenic yeast [5] that is a common member of the human gut flora. It can also survive outside the human body. It can also survive outside the human body. [ 6 ] [ 7 ] It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults.
The mechanism the human immune system has is normally to fight an infection (like Candida). Initially, Th17 cells are made by the immune system, which in turn produces interleukin-17 (IL-17). This induces inflammation and white blood cells confront infection. [9] Chronic mucocutaneous candidiasis mutations affect IL-17 by inhibiting its pathway.
The excessive tissue is composed of cellular, inflamed fibrous connective tissue. The appearance of an epulis fissuratum microscopically is an overgrowth of cells from the fibrous connective tissue. The epithelial cells are usually hyperkeratotic and irregular, hyperplastic rete ridges are often seen.
Angular cheilitis is a type of cheilitis (inflammation of the lips). [6] Angular cheilitis can be caused by infection, irritation, or allergies. [2] Infections include by fungi such as Candida albicans and bacteria such as Staph. aureus. [2]