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It is used to prevent and treat lack of calcium and vitamin D in the elderly, as well for osteoporosis in combination with other medications. [1] [2] In 2022, the combination, calcium/vitamin D was the 246th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [3] [4]
Alfacalcidol (or 1-hydroxycholecalciferol) is an analogue of vitamin D used for supplementation in humans and as a poultry feed additive.. Alfacalcidol has a weaker impact on calcium metabolism [3] and parathyroid hormone levels [4] than calcitriol; but significant effects on the immune system, including regulatory T cells. [5]
The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
These capsules deliver 2,000 IU of vitamin D, providing a potent dose to support your bone health and immune function. Kirkland's extra strength formula is ideal for those requiring higher levels ...
Caltrate [1] is a brand name calcium supplement sold by Haleon. The brand was originally owned by Pfizer (formerly Wyeth) and GSK and in Japan by Hisamitsu Pharmaceutical. The Caltrate brand is supplied in many different formulas; calcium carbonate (NOT calcium citrate) is the common ingredient serving as the calcium supplement source. [2]
"Adequate calcium and vitamin D, as part of a well-balanced diet, along with physical activity, may reduce the risk of osteoporosis." [92] Canada: Health Canada "Adequate calcium and regular exercise may help to achieve strong bones in children and adolescents and may reduce the risk of osteoporosis in older adults.