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Ototoxic medication. Ototoxicity is defined as the toxic effect on the functioning of the inner ear, which may lead to temporary or permanent hearing loss (cochleotoxic) and balancing problems (vestibulotoxic). [1] Drugs or pharmaceutical agents inducing ototoxicity are regarded as ototoxic medications. Anatomy of the human ear.
Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent. It has been recognized since the 19th century. [1]
Some over-the-counter as well as prescription drugs and certain industrial chemicals are ototoxic. Exposure to these can result in temporary or permanent hearing loss. Some medications cause irreversible damage to the ear, and are limited in their use for this reason. The most important group is the aminoglycosides (main member gentamicin). A ...
That ringing or buzzing in your ears at any given time is a symptom commonly known as tinnitus. According to the National Institutes of Health, "1 out of 10 US adults has experienced tinnitus in ...
That suggests patients with tinnitus could have damaged auditory nerves that no longer send signals to their brains, potentially resulting in brain activity that causes patients to hear sounds of ...
Hearing loss may have many different causes, but among those with tinnitus, the major cause is cochlear injury. [35] In many cases no underlying cause is identified. [2] [37] Ototoxic drugs also may cause subjective tinnitus, as they may cause hearing loss, [15] or increase the damage done by exposure to loud noise. [38]
Hearing loss is generally measured by playing generated or recorded sounds, and determining whether the person can hear them. Hearing sensitivity varies according to the frequency of sounds. To take this into account, hearing sensitivity can be measured for a range of frequencies and plotted on an audiogram.
Noise. Noise exposure is the cause of approximately half of all cases of hearing loss, causing some degree of problems in 5% of the population globally. [5] The National Institute for Occupational Safety and Health (NIOSH) recognizes that the majority of hearing loss is not due to age, but due to noise exposure.