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Enzyme inhibitors may bind reversibly or irreversibly. Irreversible inhibitors form a chemical bond with the enzyme such that the enzyme is inhibited until the chemical bond is broken. By contrast, reversible inhibitors bind non-covalently and may spontaneously leave the enzyme, allowing the enzyme to resume its function. Reversible inhibitors ...
Reverse weathering generally refers to a process of clay neoformation consuming cations and alkalinity in a way unrelated to the weathering of silicates.More specifically reverse weathering refers to the formation of authigenic clay minerals from the reaction of 1) biogenic silica with aqueous cations or cation-bearing oxides or 2) cation poor precursor clays with dissolved cations or cation ...
Chemical weathering of igneous minerals leads to the formation of secondary minerals, which constitute the weathering products of the parent minerals. Secondary weathering minerals of igneous rocks can be classified mainly as iron oxides, salts, and phyllosilicates. The chemistry of the secondary minerals is controlled in part by the chemistry ...
The irreversible inhibition did not happen, but reversible inhibition was noticed. A model has been made to explain this three-step mechanism behind the inhibitory effects of selective COX-2 inhibitors. The first step accounts for the contact of the inhibitor with the gate of the hydrophobic channel (called the lobby region). The second step ...
In contrast, reversible inhibitors bind non-covalently and different types of inhibition are produced depending on whether these inhibitors bind the enzyme, the enzyme-substrate complex, or both. Many drug molecules are enzyme inhibitors so their discovery and improvement is an active area of research in biochemistry and pharmacology.
Within the field of geology, Bowen's reaction series is the work of the Canadian petrologist Norman L. Bowen, [1] who summarized, based on experiments and observations of natural rocks, the sequence of crystallization of common silicate minerals from typical basaltic magma undergoing fractional crystallization (i.e. crystallization wherein early-formed crystals are removed from the magma by ...
In earth science, chemical weathering is attributed to organic chelating agents (e.g., peptides and sugars) that extract metal ions from minerals and rocks. [13] Most metal complexes in the environment and in nature are bound in some form of chelate ring (e.g., with a humic acid or a protein).
Competitive inhibition can be reversible or irreversible. If it is reversible inhibition, then effects of the inhibitor can be overcome by increasing substrate concentration. [8] If it is irreversible, the only way to overcome it is to produce more of the target (and typically degrade and/or excrete the irreversibly inhibited target).